The Africa Think Tank is a crucial mechanism for ARISE-NUTRINT and DASH Initiatives to foster relevant research that could lead to innovations to bridge the knowledge gap for healthy living by adolescents and youths in Africa. The value of the Africa Think Tank is expected to increase as it is used to identify challenges in policy, advances in research, knowledge gaps, implications of research findings for evidence for policy and applications to generate innovations. This effort is ultimately meant to promote development of relevant research, achieve research innovations and to enhance the capacity of participating institutions, research leaders and policy makers to work towards evidence-based policies that will promote wellbeing and healthy living by adolescents and youths in Africa.